Endocrine Abstracts

Objective: To describe body-composition, lipid profile, and health-related quality of life (HRQL) in patients with traumatic brain injury (TBI) in relation to the development of posttraumatic hypopituitarism.Design: Cross-sectional with a nested prospective sub-study.Patients: The cross-sectional cohort included 104 hospitalized patients with TBI (26F/78M; age: median 41 years (range 18–64); BMI: 25 kg/m2 (17–3...

Introduction: Subarachnoid haemorrhage (SAH) is associated with a mortality rate of 30% and the survivors face significant morbidity including fatigue, isolation, depression and sleep disorders; factors affecting general health related quality of life (QoL). QoL is also known to be decreased in pituitary-hypothalamic insufficiency and tends to improve after treatment. SAH has been suggested to be a common cause of hypopituitarism by some whereas not by others. We aimed to inve...

Objective: To estimate the occurrence of hypopituitarism 12 months following traumatic brain injury (TBI), describe the time course, evaluate the predictive value of early hormonal changes and trauma related parameters, as well as out-come.Methods Forty-six patients with TBI (mild (GCS:13–15) n=22; moderate (GCS:9–13) n=9; severe (GCS<9) n=15) were included. Patients were tested early post-injury (baseline hormone level...